sildenafil use in pulmonary arterial hypertension super study group rating
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pulmonary arterial hypertension, 23-28 and a small randomized, controlled study involving patients with idiopathic pulmonary arterial hypertension 29 suggest that sildenafil is beneficial in the treatment of pulmonary arterial hypertension. The objectives of our double-blind, placebo-controlled clinical trial In this double-blind, placebo-controlled study, we randomly assigned 278 patients with symptomatic pulmonary arterial hypertension (either idiopathic or associated with connective-tissue disease or with repaired congenital systemic-to-pulmonary shunts) to placebo or sildenafil (20, 40, or 80 mg) orally three times daily for 12 weeks. ... Citrate Therapy for Pulmonary Arterial Hypertension. ... Arterial Hypertension (SUPER) Study Group ... and Sildenafil Groups. With the use of a ... APAH = pulmonary arterial hypertension associated with connective tissue disease or repaired congenital systemic-to-pulmonary shunts; FC = functional class; HPAH = heritable pulmonary arterial hypertension; IPAH = idiopathic pulmonary arterial hypertension; SUPER = Sildenafil Use in Pulmonary Arterial Hypertension; WHO = World Health Organization. a MEDLINE Abstract. Printer-Friendly ... citrate in pulmonary arterial hypertension: the SUPER-2 study. ... (SUPER-1 [Sildenafil Use in Pulmonary Arterial ... Rationale: Although the phosphodiesterase type 5 inhibitors sildenafil and tadalafil have demonstrated efficacy in patients with pulmonary arterial hypertension (PAH), monotherapy with these agents has not been conclusively shown to reduce clinical worsening events. Sildenafil (Revatio) received approval for treatment of pulmonary arterial hypertension based upon the results of the SUPER1 study that randomized patients to sildenafil 20, 40 or 80 mg tid or matching placebo. 1 For the open label extension study, all patients received 80 mg tid. Sildenafil in severe pulmonary hypertension ... Use in Pulmonary Arterial Hypertension (SUPER ... Hypertension (SUPER) study group. Sildenafil ... A New START for Sildenafil in Pediatric Pulmonary ... against the use of sildenafil in ... Arterial Hypertension (SUPER) Study Group. Therapeutic Class Overview Oral Pulmonary Arterial Hypertension ... oral pulmonary arterial hypertension ... Hypertension (SUPER) Study Group. Sildenafil ... cialis pill image
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